Propionibacterium acnes in Human Health and Disease
نویسندگان
چکیده
1 Centre for Stratified Medicine, School of Biomedical Sciences, University of Ulster, Altnagelvin Hospital, Londonderry BT47 6SB, UK 2Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast BT7 9BL, UK 3Department of Human Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo 113-8519, Japan 4 School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK 5Department of Dermatology, Harrogate and District NHS Foundation, Harrogate HG2 7SX, UK
منابع مشابه
Determination of antibiotic susceptibility and Minimum Inhibitory Concentration (MIC) of the Propionibacterium acnes to the prevalent antibiotics in the treatment of Acne vulgaris
ABSTRACTPropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. Today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. In order to determine the antibiotic resistance of the P.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...
متن کاملبررسی اثر ضد میکروبی عصاره‌ی اتانولی برگ درخت گردو بر روی پروپیونی باکتریوم آکنه
Background and Objective: Acne is one of the medical problems and propionibacterium acnes is the pathogenic agent that has received a considerable attention. Different parts of Juglans regia have been shown to have antibacterial activity on many bacteria. Its leaves have antioxidant property and if it shows antibacterial effect on propionibacterium acnes, it might be an alternative drug for the...
متن کاملPropionibacterium acnes strain populations in the human skin microbiome associated with acne
The human skin microbiome has important roles in skin health and disease. However, bacterial population structure and diversity at the strain level is poorly understood. We compared the skin microbiome at the strain level and genome level of Propionibacterium acnes, a dominant skin commensal, between 49 acne patients and 52 healthy individuals by sampling the pilosebaceous units on their noses....
متن کاملStrain-Level Differences in Porphyrin Production and Regulation in Propionibacterium acnes Elucidate Disease Associations
Propionibacterium acnes is an important skin commensal, but it is also considered a pathogenic factor in several diseases including acne vulgaris, the most common skin disease. While previous studies have revealed P. acnes strain-level differences in health and disease associations, the underlying molecular mechanisms remain unknown. Recently, we demonstrated that vitamin B12 supplementation in...
متن کاملMultilocus sequence typing and phylogenetic analysis of Propionibacterium acnes.
Propionibacterium acnes is a commensal of human skin but is also implicated in the pathogenesis of acne vulgaris, in biofilm-associated infections of medical devices and endophthalmitis, and in infections of bone and dental root canals. Recent studies associate P. acnes with prostate cancer. As the species includes evolutionary lineages with distinct association with health and disease, there i...
متن کاملOver a Decade of recA and tly Gene Sequence Typing of the Skin Bacterium Propionibacterium acnes: What Have We Learnt?
The Gram-positive, anaerobic bacterium Propionibacterium acnes forms part of the normal microbiota on human skin and mucosal surfaces. While normally associated with skin health, P. acnes is also an opportunistic pathogen linked with a range of human infections and clinical conditions. Over the last decade, our knowledge of the intraspecies phylogenetics and taxonomy of this bacterium has incre...
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ورودعنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013